Multiparametric ultrasound for the assessment of testicular lesions with negative tumoral markers

作     者：Hui Liu Lin Dong Li-Hua Xiang Guang Xu Jing Wan Yan Fang Shi-Si Ding Ye Jin Li-Ping Sun Hui-Xiong Xu 

作者机构：Department of Medical UltrasoundCenter of Minimally Invasive Treatment for TumorShanghai Tenth People's HospitalSchool of MedicineTongji UniversityShanghai 200072China Ultrasound Research and Education InstituteClinical Research Center for Interventional MedicineSchool of MedicineTongji UniversityShanghai 200072China Shanghai Engineering Research Center of Ultrasound Diagnosis and TreatmentShanghai 200072China National Clinical Research Center for Interventional MedicineShanghai 200072China Department of UltrasoundZhongshan HospitalFudan UniversityInstitute of Ultrasound in Medicine and EngineeringShanghai 200032China 

出 版 物：《Asian Journal of Andrology》 (亚洲男性学杂志（英文版）)

年 卷 期：2023年第25卷第1期

页      面：50-57页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

基　　金：supported in part by the National Natural Science Foundation of China (No.81801700) the Fundamental Research Funds for the Central Universities (No.ZD-11-202151) the Shanghai Municipal Health Commission (No.2019LJ21 and No.SHSLCZDZK03502) the Science and Technology Commission of Shanghai Municipality (No.19DZ2251100) the Scientific Research and Development Fund of Zhongshan Hospital of Fudan University (No.2022ZSQD07) 

主　　题：diagnosis histology testicular diseases ultrasound 

摘      要：The purpose of this study was to evaluate the diagnostic performance of multiparametric ultrasound(mpUS;grayscale US,color Doppler US,strain elastography,and contrast-enhanced US)in the assessment of testicular lesions with negative tumoral *** imaging data,patient age,serum tumor markers,scrotal pain,cryptorchidism,and related clinical information were retrospectively collected for patients who underwent mpUS examination between January 2013 and December *** results or follow-up examinations were used as the reference *** total,83 lesions from 79 patients were included in the ***-six patients were finally diagnosed with benign tumors,and 23 patients were ultimately diagnosed with malignant ***-square tests or Fisher s exact tests were used to assess the difference between the two *** multivariate logistic regression analysis showed that lesion diameter(odds ratio[OR]=1.072,P=0.005),vascularization on color Doppler US(OR=4.066,P=0.001),and hyperenhancement during the early phase(OR=6.465,P=0.047)were significant independent risk factors for malignancy;however,when compared with neoplastic lesions,pain(OR=0.136,P0.001),absence of vascularization on color Doppler US(OR=1.680,P=0.042),and nonenhancement during the late phase(OR=3.461,P=0.031)were strongly associated with nonneoplastic *** features are useful for differentiating testicular lesions with negative tumoral markers and improving the preoperative diagnosis,which may avoid inappropriate radical orchiectomy.