Liver injury and dietary supplements:Does hydroxycitric acid trigger hepatotoxicity?

作     者：Andrea Zovi Roberto Langella Andrea Nisic Antonio Vitiello Umberto M.Musazzi a Andrea Zovi;Roberto Langella;Andrea Nisic;Antonio Vitiello;Umberto M.Musazzi

作者机构：Department of Pharmaceutical SciencesUniversity of MilanVia G.ColomboMilan 71-20133Italy Italian Society of Hospital Pharmacy(SIFO)SIFO Secretariat of the Lombardy RegionVia Carlo Farini81Milan 20159Italy Regional Pharmacovigilance CenterLombardy RegionPiazza Cittàdi Lombardia1Milan 20124Italy Pharmaceutical DepartmentUSL Umbria 1Via Guerriero Guerra21Perugia 06127Italy 

出 版 物：《Journal of Integrative Medicine》 (结合医学学报（英文版）)

年 卷 期：2022年第20卷第5期

页      面：473-475页

核心收录：

学科分类：0832[工学-食品科学与工程（可授工学、农学学位）] 1002[医学-临床医学] 08[工学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 083201[工学-食品科学] 10[医学] 

主　　题：Weight loss Garcinia cambogia Hydroxycitric acid Hepatotoxicity Adverse event 

摘      要：Rising rates of obesity has increased the global use of herbal supplements intended to control ***,taking these preparations without appropriate medical supervision could increase the risk of manifestation of side effects,especially at the hepatic *** literature,different cases of acute liver injury consequent to the use of food supplements containing Garcinia cambogia and hydroxycitric acid are *** letter aims to review the most recent literature that analysed the herb-induced liver disease due to the use of hydroxycitric acid,from the first alert coming from the European Food and Drug Administration in 2009,to the last recent European food alerts from 2020 to *** is noteworthy that in some cases it demonstrated the relationship between hydroxycitric acid and ***,there is a need to draw more attention to the relationship between a safe use and a more awareness in the intake of these supplements,to preserve the safety of the consumers who increasingly purchase food supplements,products that have only nutritive properties and are never curative.