Meaningful Contact Estimates among Children in a Childcare Centre with Applications to Contact Matrices in Infectious Disease Modelling

作     者：Darren Flynn-Primrose Nickolas Hoover Zahra Mohammadi Austin Hung Jason Lee Miggi Tomovici Edward W. Thommes Dion Neame Monica G. Cojocaru Darren Flynn-Primrose;Nickolas Hoover;Zahra Mohammadi;Austin Hung;Jason Lee;Miggi Tomovici;Edward W. Thommes;Dion Neame;Monica G. Cojocaru

作者机构：Department of Mathematics & Statistics University of Guelph Guelph ON Canada Sanofi Canada Laval Canada Department of Pediatrics McMaster University Hamilton ON Canada 

出 版 物：《Journal of Applied Mathematics and Physics》 (应用数学与应用物理（英文）)

年 卷 期：2022年第10卷第5期

页      面：1525-1546页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Contact Matrices Agent Based Model of Child Care High Time Resolution Model Infectious Disease Applications 

摘      要：We present a mathematical model of a day care center in a developed country (such as Canada), in order to use it for the estimation of individual-to-individual contact rates in young age groups and in an educational group setting. In our model, individuals in the population are children (ages 1.5 to 4 years) and staff, and their interactions are modelled explicitly: person-to-person and person-to-environment, with a very high time resolution. Their movement and meaningful contact patterns are simulated and then calibrated with collected data from a child care facility as a case study. We present these calibration results as a first part in the further development of our model for testing and estimating the spread of infectious diseases within child care centers.