雌性GK糖尿病大鼠的核糖,AGEs和转酮酶变化

作     者：CAO Xiao YU Le-Xiang WEI Yan QU Mei-Hua HE Rong-Qiao 

作者机构：College of Basic MedicineSouthwest Medical UniversityLuzhou 646000China Institute of BiophysicsChinese Academy of SciencesBeijing 100101China Translational Medical CenterWeifang Second People’s HospitalWeifang 261041China University of Chinese Academy of SciencesBeijing 100049China 

出 版 物：《生物化学与生物物理进展》 (Progress In Biochemistry and Biophysics)

年 卷 期：2022年第49卷第5期

页      面：949-952页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：supported by a grant from Beijing Brain Project(Z161100000217141) 

主　　题：metabolism hypertensive diabetes 

摘      要：Dear Editor,Type 2 diabetes is a chronic disease characterized by high glucose levels in the ***,it has been found that type 2 diabetic patients suffer from glucose and ribose dysmetabolism[1-3].The GotoKakizaki(GK)rat is a nonobese,nonhypertensive model of type 2 diabetes,which,like humans,shares a susceptibility locus on chromosome 10[4-5].