Construction of nanocarriers based on nucleic acids and their applications in nanobiology delivery systems

作     者：Yingshu Guo Xiuping Cao Xiaofei Zheng Sk Jahir Abbas Juan Li Weihong Tan Yingshu Guo;Xiuping Cao;Xiaofei Zheng;Sk Jahir Abbas;Juan Li;Weihong Tan

作者机构：Shandong Provincial Key Laboratory of Molecular Engineering School of Chemistry and Chemical EngineeringQilu University of Technology (Shandong Academy of Sciences) School of Chemistry and Chemical Engineering Linyi University Institute of Molecular MedicineState Key Laboratory of Oncogenes and Related Genes Renji Hospital Shanghai Jiao Tong University School of MedicineCollege of Chemistry and Chemical Engineering Shanghai Jiao Tong University Institute of Cancer and Basic MedicineChinese Academy of Sciences The Cancer Hospital of the University of Chinese Academy of Sciences 

出 版 物：《National Science Review》 (国家科学评论(英文版))

年 卷 期：2022年第9卷第5期

页      面：181-195页

核心收录：

学科分类：0710[理学-生物学] 100702[医学-药剂学] 1007[医学-药学(可授医学、理学学位)] 1006[医学-中西医结合] 0805[工学-材料科学与工程（可授工学、理学学位）] 0901[农学-作物学] 0703[理学-化学] 0836[工学-生物工程] 100602[医学-中西医结合临床] 10[医学] 

基　　金：supported by the Development Plan of the Youth Innovation Team in Colleges and Universities of Shandong Province (2020KJC003) the Natural Science Foundation of Shandong Province of China (ZR2016JL010) the Key Technology Research and Development Program of Shandong Province(2018GSF118172) the National Natural Science Foundation of China (21575056) 

主　　题：nanocarriers based on nucleic acids biosensing targeted delivery cell 

摘      要：In recent years,nanocarriers based on nucleic acids have emerged as powerful and novel nanocarriers that are able to meet the demand for cancer-cell-specific *** dynamics analysis revealed good bio compatibility,low toxicity and programmable structures,and their advantages include controllable size and *** development of novel hybrids has focused on the distinct roles of biosensing,drug and gene delivery,vaccine transport,photosensitization,counteracting drug resistance and functioning as carriers and logic *** review is divided into three parts:(ⅰ) DNA nanocarriers,(ⅱ) RNA nanocarriers and(ⅲ) DNA/RNA hybrid nanocarriers and their applications in nanobiology delivery *** also provide perspectives on possible future directions for growth in this field.