Status of vitamin E and reduced glutathione in semen of oligozoospermic and azoospermic patients

作     者：A.Bhardwaj A.Verma S.Majumdar K.L.Khanduja 

作者机构：Departments of Biophysics and Experimental MedicinePostgraduate Institute of Medical Education&ResearchChandigarhIndia 

出 版 物：《Asian Journal of Andrology》 (亚洲男性学杂志(英文版))

年 卷 期：2000年第2卷第3期

页      面：225-228页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：oligospermia glutathione vitamin E semen 

摘      要：Aim:To investigate the status of seminal plasma reduced glutathione(GSH)and vitamin E in three different condi-tions of spermatogenesis:azoospermia,oligozoospermia and ***:Reduced glutathione wasmeasured in the seminal plasma by the method of Moron et al(1979),and vitamin E estimation was performed by themethod of Taylor et al(1976).Results:Vitamin E levels in seminal plasma of oligospermic and azoospennic sam-ples were significantly decreased to 65.54%and 66.04%respectively as compared to the normospermic *** reduced glutathione were also significantly decreased in oligospermic and azoospennic group,and the reduction inazoospermic group(76.73%)was more pronounced than oligozoospermic group(62.07%).*** de-crease in reduced glutathione,an endogenous antioxidant,levels in azoospermic and oligozoospermic conditions maycause dismption in the membrane integrity of spermatozoa as a consequence of increased oxidative stress.