A review of the current evidence for the role of minimally invasive pancreatic surgery following neo-adjuvant chemotherapy

作     者：Francis P.Robertson Rowan W.Parks Francis P.Robertson;Rowan W.Parks

作者机构：Department of Hepatobiliary and Transplant SurgeryFreeman HospitalNewcastleUnited Kingdom Department of Clinical SurgeryRoyal Infirmary of EdinburghEdinburghUnited Kingdom Division of Surgical and Interventional ScienceRoyal Free CampusUniversity College LondonLondonUnited Kingdom 

出 版 物：《Laparoscopic, Endoscopic and Robotic Surgery》 (腔镜、内镜与机器人外科（英文）)

年 卷 期：2022年第5卷第2期

页      面：47-51页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Pancreatic resection Minimally invasive Robotic Neo-adjuvant chemotherapy 

摘      要：Objective:Surgical resection of pancreatic cancer remains the only potentially curative treatment for pancreatic ductal *** robotic platform has been introduced to surgical practice and recent large studies from national registries have demonstrated similar or improved peri-operative outcomes compared to the standard open ***-adjuvant chemotherapy is increasingly being offered to patients with borderline resectable/locally advanced disease but this has led to more challenging *** of patients undergoing minimally invasive resection following neo-adjuvant chemotherapy remain *** aim of this review is to assess the current evidence for the peri-operative safety and long-term oncological outcomes associated with minimally invasive pancreatic resection following neo-adjuvant ***:Medline,Embase and Cochrane Central Register for Clinical Trials were searched up until 31st October *** search terms include“minimally invasive,“robotic,“laparoscopic,“pancreatectomy,“pancreatic resection,“whipple s pancreaticoduodenectomy,“distal pancreatectomy,“chemotherapy,“neo-adjuvant chemotherapy,“radiotherapy,“neo-adjuvant chemoradiotherapy,“induction therapy,and“conversion surgery.All studies including patients undergoing pancreatic resections were *** which did not clearly state the approach to resection(minimally invasive or open)were ***:Seventy-eight studies were identified of which 8 compared open and minimally invasive resection following neo-adjuvant *** was insufficient data to perform a *** surgery was associated with lower blood loss and shorter length of hospital ***-year overall survival rates were similar between patients who underwent robotic or open resection however the robotic approach was associated with higher lymph node yield and a lower R1 resection ***:Currently the evidence for minimally invasive surgery foll