Therapeutic peptides: current applications and future directions

作     者：Lei Wang Nanxi Wang Wenping Zhang Xurui Cheng Zhibin Yan Gang Shao Xi Wang Rui Wang Caiyun Fu 

作者机构：Zhejiang Provincial Key Laboratory of Silkworm Bioreactor and BiomedicineCollege of Life Sciences and MedicineZhejiang Sci-Tech University310018 HangzhouChina State Key Laboratory Cultivation Base for TCM Quality and EfficacyNanjing University of Chinese MedicineNanjing 210046China Department of OncologyNo.903 Hospital of PLA Joint Logistic Support ForceXi Hu Affiliated Hospital of Hangzhou Medical CollegeHangzhou 310013China Key Laboratory of Preclinical Study for New Drugs of Gansu ProvinceSchool of Basic Medical Sciences&Research Unit of Peptide ScienceChinese Academy of Medical Sciences2019RU066Lanzhou University730000 LanzhouChina Institute of Materia MedicaChinese Academy of Medical Sciences and Peking Union Medical College100050 BeijingChina 

出 版 物：《Signal Transduction and Targeted Therapy》 (信号转导与靶向治疗（英文）)

年 卷 期：2022年第7卷第3期

页      面：686-712页

核心收录：

学科分类：0710[理学-生物学] 08[工学] 0805[工学-材料科学与工程（可授工学、理学学位）] 

基　　金：This work was supported by Zhejiang Provincial Natural Science Foundation of China under Grant No.LD22H310004,the National Natural Science Foundation of China(No.81770176) the"Pioneer"and"Leading Goose"R&D Program of Zhejiang(No.2022C03005) the special support plan for Zhejiang Province high-level talents(No.2019R52011) the Zhejiang Provincial Natural Science Foundation of China under Grant No.LQ20H300005 Program of Xinmiao Talents in Zhejiang Province(2021R406062). 

主　　题：directions overcome continued 

摘      要：Peptide drug development has made great progress in the last decade thanks to new production,modification,and analytic technologies.Peptides have been produced and modified using both chemical and biological methods,together with novel design and delivery strategies,which have helped to overcome the inherent drawbacks of peptides and have allowed the continued advancement of this field.