Pointing fingers at blood contact:mechanisms of subventricular zone neural stem cell differentiation

作     者：Subash C.Malik Yu-Hsuan Chu Christian Schachtrup Subash C.Malik;Yu-Hsuan Chu;Christian Schachtrup

作者机构：Institute of Anatomy and Cell BiologyFaculty of MedicineUniversity of FreiburgFreiburgGermany Faculty of BiologyUniversity of FreiburgFreiburgGermany Center for Basics in NeuroModulation(NeuroModulBasics)Faculty of MedicineUniversity of FreiburgFreiburgGermany 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2023年第18卷第1期

页      面：137-138页

核心收录：

学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学] 

基　　金：support from the German Research Foundation Grants SCHA 1442/8-1  and 1442/9-1 to CS 

主　　题：ventricular neural injury 

摘      要：The limited ability of the central nervous system(CNS)to regenerate in adult mammals after injury or disease is a significant ***,neural stem/progenitor cells(NSPCs)offer great promise for regenerating the *** or transplanted NSPCs contribute to repair processes,but their differentiation and function are abnormal in CNS injury and *** main reasons for these abnormalities are changes in the extracellular environment in the injured CNS that affect signaling pathways and transcriptional regulation in NSPCs.