Ginger-indirect moxibustion plus acupuncture versus acupuncture alone for chronic fatigue syndrome:a randomized controlled trial

作     者：MA Tingting WU Jie YANG Lijie FENG Fen YANG Huilin ZHANG Jinhua ZHONG Yanjin NING Qing HUANG Lirong LIN Youbing YAN Jue CHEN Guiquan HOU Tianshu WANG Li REN Yuanfang TAN Jing MA Tingting;WU Jie;YANG Lijie;FENG Fen;YANG Huilin;ZHANG Jinhua;ZHONG Yanjin;NING Qing;HUANG Lirong;LIN Youbing;YAN Jue;CHEN Guiquan;HOU Tianshu;WANG Li;REN Yuanfang;TAN Jing

作者机构：Center of Preventive MedicineHospital of Chengdu University of Traditional Chinese MedicineChengdu 610075China College of Acupuncture and TuinaChengdu University of Traditional Chinese MedicineChengdu 610075China Department of acupunctureCenter of Preventive MedicineAffiliated TCM Hospital of Southwest Medical UniversityLuzhou 646600China Center of Preventive MedicineChengdu Integrated TCM and Western Medicine HospitalChengdu 610021China Center of Chinese Evidence-Based MedicineSichuan University West China HospitalChengdu 610041China 

出 版 物：《Journal of Traditional Chinese Medicine》 (中医杂志（英文版）)

年 卷 期：2022年第42卷第2期

页      面：242-249页

核心收录：

学科分类：1005[医学-中医学] 1002[医学-临床医学] 100512[医学-针灸推拿学] 10[医学] 

基　　金：Supported by the Science and Technology Support Program of Sichuan Province Science and Technology Agency:Clinical Researches of Acupuncture for“Unhealthy Status”Based on the TCM Theory of“All Diseases Originate from Qi’s Problem”(No.2014SZ0152)。 

主　　题：ginger-indirect moxibustion fatigue syndrome chronic treatment outcome safety randomized controlled trial 

摘      要：OBJECTIVE:To assess the efficacy and safety of gingerindirect moxibustion for chronic fatigue syndrome(CFS).METHODS:In this central randomized,controlled trial,290 CFS participants were recruited and randomly allocated to group A(ginger-indirect moxibustion plus acupuncture)or group B(acupuncture alone).The study consisted of a treatment period of 8 weeks with a total of 24 treatments(3 sessions per week,every other day),and a follow-up period of 12 weeks.The outcome was measured by Fatigue Severity Scale(FSS),Psychological Health Report(SPHERE),the Self-rating depression scale(SDS)and the Hamilton anxiety scale(HAMA)at baseline,2,4,6,8,12 and 20 weeks.RESULTS:With the treatment undergoing,the changes of FSS,SPHERE,SDS and HAMA scores in both groups increased gradually,and the effect maintained at the 12th week.Between groups,significantly higher score changes were seen in group A in FSS after 4 weeks treatment(11.94 vs 9.12,95%CI:0.94,4.7)and in SPHERE after 2 weeks treatment(3.7 vs 2.27,95%CI:0.56,2.31).But for SDS and HAMA,the improvement did not differ significantly between groups.No severe adverse events were reported.CONCLUSION:Ginger-indirect moxibustion is a safe and effective intervention to relieve fatigue and accompanying physical symptoms of CFS.