Impact of Coronary Artery Anatomy in Arterial Switch Operation:In-hospital and Post-discharge Outcomes

作     者：Shu-yuan WANG Qing-yu ZENG Li ZHANG Qing LV Ming-xing XIE Shu-yuan WANG;Qing-yu ZENG;Li ZHANG;Qing LV;Ming-xing XIE

作者机构：Department of UltrasoundUnion HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Clinical Research Center for Medical Imaging in Hubei ProvinceWuhan 430022China Hubei Province Key Laboratory of Molecular ImagingWuhan 430022China Shenzhen Huazhong University of Science and Technology InsitituteShenzhen 518057China 

出 版 物：《Current Medical Science》 (当代医学科学（英文）)

年 卷 期：2022年第42卷第3期

页      面：642-649页

核心收录：

学科分类：1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：the National Natural Science Foundation of China(No.81727805 and No.82001854) the Shenzhen Science and Technology(No.SGDX20190917094601717 and No.JCYJ20210324141216040) 

主　　题：congenital heart disease complex coronary artery early mortality late mortality learning curve 

摘      要：Objective The influence of the coronary artery anatomy on the prognosis of patients receiving an arterial switch operation(ASO)is currently controversial,and the risk factors for this operation may change in more complicated *** study aimed to investigate the influence of coronary artery anomalies on the in-hospital and post-discharge outcomes of ASO in patients with transposition of the great arteries(TGA)and Taussig-Bing anomaly(TBA).Methods We retrospectively reviewed 206 patients who underwent ASO from January 2007 to December *** median age at operation was 33[interquartile range(IQR):20–71]*** follow-up time was 7.2 years(IQR:4.0–10.3 years).Results Coronary anomalies were present in 86 patients(41.7%),with 9(4.4%)of them having a single coronary *** coronary features included intramural courses in 5(2.4%)patients,ostial stenosis in 1(0.5%)patient,and accessory coronary artery orifices in 5(2.4%)*** were 32(15.5%)in-hospital deaths and 8(4.6%)post-discharge deaths,yielding an overall survival of 81.3%,80.7%and 79.9%at 1,5 and 10 years,*** due to ASO has been drastically decreased since *** with a single coronary artery had higher rate of in-hospital mortality,but this finding was not statistically *** earlier surgical era(OR:2.756)and a longer cardiopulmonary bypass time(OR:2.336)were significantly associated with in-hospital mortality,while coronary patterns were *** intramural coronary artery(HR:10.034)and a patient age of older than 1 year at the time of ASO(HR:9.706)were independent predictors of post-discharge *** ASO remains the procedure of choice for TGA with coronary anomalies with acceptable in-hospital and post-discharge outcomes in terms of overall survival and freedom of ***,intramural coronary artery is an independent risk factor for post-discharge *** surgery within the 1st year of life helps improve overall m