*** endothelium decompensation in patients with chronic hypotony after glaucoma surgery
作者机构：Department of MedicineMcGill UniversityMontrealQCCanada Department of OphthalmologyUniversity of MontrealMontrealQCCanada Maisonneuve Rosemont Hospital Research CentreMontrealQCCanada
出 版 物：《Annals of Eye Science》 (眼科学年鉴（英文）)
年 卷 期：2019年第1期
页 面：203-203页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Hypotony glaucoma corneal decompensation
摘 要：Background:To describe and discuss four cases of corneal endothelial decompensation secondary to chronic hypotony after glaucoma ***:A retrospective case review was undertaken for four4 patients over a 20-year period from a single glaucoma *** data were collected from the clinical records of each subject included in the study:(I)patient demographic characteristics;(II)past ocular history and indication for surgery;(III)ocular vitals;(IV)complications from glaucoma surgery;(V)corneal exam and pathology and the indication for corneal transplant;(VI)surgical interventions during the period of ***:Four patients sustained chronic hypotony(range,3-18 years)after glaucoma *** most of these eyes during relative hypotony,long thin vertical folds were often noted in the superficial cornea(possibly involving Bowman’s layer and the epithelium),leading to fluorescein *** subsequently developed marked corneal pathologies including stromal edema,diminished endothelial density,microcyst formation,corneal erosion,Descemet folds,superficial punctate keratitis and bullous *** of them received Descemet stripping automated endothelial keratoplasty(DSAEK)and regained functional ***:This case series demonstrates a unique clinical entity in which corneal endothelial demise developed in the context of chronic *** mechanism underlying this entity,which we term“chronic hypotony corneal endotheliopathy(CHCE),remains *** hypothesize that it can be due to a combination of tectonic instability and energy disturbance of the *** clinical practice,it is important to monitor endothelial cell count in patients with persistent hypotony,especially those who had procedures such as glaucoma surgery that can precipitate endothelial injury.
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