Coexistence of meningioma and other intracranial benign tumors in non-neurofibromatosis type 2 patients:A case report and review of literature

作     者：Tian-Hao Hu Run Wang Hai-Yun Wang Yi-Fu Song Juan-Han Yu Zi-Xun Wang Yu-Zhou Duan Ting Liu Sheng Han 

作者机构：Department of NeurosurgeryThe First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina Department of PathologyChina Medical UniversityShenyang 110001Liaoning ProvinceChina Department of RadiologyThe First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina 

出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期：2022年第10卷第13期

页      面：4249-4263页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：Supported by the LiaoNing Revitalization Talents Program,No.XLYC1807253 the National Natural Science Foundation of China,No.81772653 

主　　题：Meningioma Sub-ependymoma Pituitary adenoma Coexisting tumors Case report 

摘      要：BACKGROUND The coexistence of meningioma and other intracranial primary benign tumors is rare,especially in non-neurofibromatosis type 2,and there is limited guidance for the management of such ***,we report a series of 5 patients with concomitant meningioma and other intracranial benign tumors,including subependymoma and pituitary *** SUMMARY Five non-neurofibromatosis type 2 patients with simultaneous occurrence of meningioma and other intracranial benign tumors were retrospectively *** patients had no history of previous *** clinical features,pre-and postoperative imaging,surgical procedure and pathological findings were extracted from electronic medical *** were 4 female patients(80%)and 1 male patient(20%).The mean age was 42.8 years(range:29-52 years).The coexisting tumors included subependymoma in 1 case(20%)and pituitary adenoma in 4 cases(80%).The most common clinical symptom was headache(3/5,60%).Four patients(80%)underwent *** patient(20%)underwent transsphenoidal surgery followed by transcranial *** tumor diagnoses were confirmed by histopathological *** mean follow-up was 38.8 mo(range:23-96 mo),and all 5 patients were in a stable condition at the last *** The simultaneous occurrence of meningioma and other intracranial benign tumors is a rare clinical *** examination is necessary for the accurate *** should select the appropriate surgical strategy according to the clinical features of each patient,which may provide a more favorable prognosis for individual patients.