Pediatric uveitis:EYE-Q and metrics beyond visual acuity

作     者：Joseph M.McDonald Steven Yeh Sheila T.Angeles-Han 

作者机构：Division of RheumatologyCincinnati Children’s Hospital Medical CenterCincinnatiOHUSA Emory Eye CenterEmory University School of MedicineAtlantaGAUSA Division of OphthalmologyCincinnati Children’s Hospital Medical CenterCincinnatiOHUSA Department of Pediatrics and OphthalmologyUniversity of CincinnatiCincinnatiOHUSA 

出 版 物：《Annals of Eye Science》 (眼科学年鉴（英文）)

年 卷 期：2020年第5卷第2期

页      面：101-108页

学科分类：1002[医学-临床医学] 100202[医学-儿科学] 10[医学] 

基　　金：STA His supported by Award Number R01EY030521 from the National Eye Institute 

主　　题：Uveitis health-related quality of life(HR-QOL) vision-related quality of life(VR-QOL) 

摘      要：Pediatric uveitis is an inflammatory ocular disease that can lead to sight-threatening *** patients have distinct challenges in the diagnosis and management of uveitis,secondary to difficulties in performing ophthalmic examinations in young children,delayed diagnosis due to lack of adherence with recommended screening schedules,medication side-effects,and increased burden of disease into *** of outcomes in pediatric uveitis has traditionally relied upon the ophthalmic examination and general quality of life(QOL)***,the ophthalmic examination does not take into account the impact of uveitis on a child’s QOL and general QOL measures do not adequately assess the specific effects of *** vision-related quality of life(VR-QOL)instruments have been used to measure outcomes in both adults and children including:the National Eye Institute Visual Function Questionnaire(NEI VFQ-25),Vision-related Quality of Life of Children and Young People(VQoL_CYP),the Children’s Visual Function Questionnaire(CVFQ),and the Effect of Youngsters’Eyesight on Quality of Life(EYE-Q).However,the NEI VFQ-25 is not a valid or applicable measure in children,and the VQoL_CYP and CVFQ are not uveitis specific and may not characterize disease specific *** EYE-Q is the only uveitis-specific pediatric questionnaire that measures visual functioning and VR-QOL in 5-18 years old children and adolescents with *** has been shown to be a valid and reliable assessment tool in several cohorts of children with uveitis.A comprehensive assessment of the impact of uveitis on a child that includes a vision-specific measure,such as the EYE-Q,allows for better understanding of the true burden of uveitis in *** this review,we describe traditional outcome measures in uveitis studies,general QOL measures and vision-specific measures in adults and in children.