Corrosion behavior,antibacterial ability,and osteogenic activity of Zn-incorporated Ni-Ti-O nanopore layers on NiTi alloy

作     者：Yonghua Sun Yuyu Zhao He Zhang Youjie Rong Runhua Yao Yi Zhang Xiaohong Yao Ruiqiang Hang Yonghua Sun;Yuyu Zhao;He Zhang;Youjie Rong;Runhua Yao;Yi Zhang;Xiaohong Yao;Ruiqiang Hang

作者机构：Laboratory of Biomaterial Surfaces&InterfacesInstitute of New Carbon MaterialsCollege of Materials Science and EngineeringTaiyuan University of TechnologyTaiyuan 030024China 

出 版 物：《Journal of Materials Science & Technology》 (材料科学技术（英文版）)

年 卷 期：2022年第97卷第2期

页      面：69-78页

核心收录：

学科分类：080503[工学-材料加工工程] 08[工学] 0806[工学-冶金工程] 0805[工学-材料科学与工程（可授工学、理学学位）] 

基　　金：financially supported by the Fund for Shanxi“1331 Project”Key Innovative Research Team(No.PY201809) Program for the Innovative Talents of Higher Education Institutions of Shanxi(PTIT) Natural Science Foundation of Shanxi Province(No.201801D121093)。 

主　　题：Nickel-titanium alloy Anodization Corrosion behavior Antibacterial ability Osteogenic activity 

摘      要：Development of bone fixation devices with excellent corrosion resistance,antibacterial ability,and osteogenic activity is critical for promoting fracture healing.In this study,Zn-incorporated nanopore(NP)layers were prepared on the NiTi alloy through anodization and hydrothermal treatment.Results show that Zn can be evenly incorporated into the NP layers in the form of ZnTiO_(2).The Zn-incorporated samples exhibit good corrosion resistance and significantly reduce Ni^(2+)release.Meanwhile,the samples can continuously release Zn^(2+),which is responsible for excellent long-term antibacterial ability.Furthermore,the synergetic effect of Zn^(2+) release and nanoporous structure of the NP layers endues the NiTi alloy excellent osteogenic activity,as verified by upregulated alkaline phosphatase activity,secretion of type I collagen,and extracellular matrix mineralization.Therefore,Zn-incorporated Ni-Ti-O NP layers have great potential as biomedical coatings of NiTi-based implant materials.