AB066. Duration dependent visual plasticity via monocular deprivation

作     者：Seung Hyun Min Alex Baldwin Alexandre Reynaud Robert F.Hess 

作者机构：Department of OphthalmologyMcGill Vision ResearchMcGill UniversityMontrealQCCanada 

出 版 物：《Annals of Eye Science》 (眼科学年鉴（英文）)

年 卷 期：2018年第1期

页      面：472-472页

学科分类：08[工学] 0812[工学-计算机科学与技术（可授工学、理学学位）] 

主　　题：Neuroplasticity ocular dominance monocular deprivation 

摘      要：Background:Short-term monocular deprivation has been recently shown to temporarily increase the sensitivity of the patched *** studies have patched subjects for an arbitrary period of 2.5 hours,but for no principled *** goal is to show a relationship,if any,between the length of patching duration and the strength of its ***:We tested nine subjects with three different patching durations:1-,2-,*** of the nine subjects were patched for *** deprivation was achieved by the use of a translucent eyepatch.A session included two rounds of baseline testing of interocular eye balance,patching,and post-patching *** post-patching test occurred at 0,3,6,12,24,48,60 and 96 minutes after patching to track the patching effect over *** subject performed two sessions per ***:One-hour patching produced a small shift in ocular dominance.A larger shift occurred from 2-hour patching,but 3-hour patching produced a comparable effect to the one measured after 2-hour ***:These results show a saturation of the patching effect beyond 2-hour ***,we believe that 2-hour patching duration is the optimal duration for eye dominance changes induced by monocular deprivation.