Headspace Solid-Phase Micro-Extraction Gas Chromatography/Mass Spectrometry(HS-SPME-GC/MS)-Based Untargeted Metabolomics Analysis for Comparing the Volatile Components from 12 Panax Herbal Medicines

作     者：Simiao Wang Xiaohang Li Meiting Jiang Xinlong Wu Yuying Zhao Meiyu Liu Xiaoyan Xu Huimin Wang Hongda Wang Heshui Yu Wenzhi Yang 

作者机构：State Key Laboratory of Component-Based Chinese Medicine&Tianjin Key Laboratory of TCM Chemistry and AnalysisTianjin University of Traditional Chinese MedicineTianjin301617China College of Pharmaceutical Engineering of Traditional Chinese MedicineTianjin University of Traditional Chinese MedicineTianjin301617China 

出 版 物：《Phyton-International Journal of Experimental Botany》 (国际实验植物学杂志（英文）)

年 卷 期：2022年第91卷第7期

页      面：1353-1364页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：National Natural Science Foundation of China(Grant No.81872996) Natural Science Foundation of Tianjin of China(Grant No.20JCYBJC00060) 

主　　题：Headspace solid-phase micro-extraction gas chromatography/mass spectrometry Panax volatile component untargeted metabolomics 

摘      要：Quality control of ginseng currently is mainly based on ginsenoside analysis,but rarely focuses on the volatile organic *** the current work,an untargeted metabolomics approach,by headspace solid-phase micro-extraction gas chromatography/mass spectrometry(HS-SPME-GC/MS),was elaborated and further employed to holistically compare the compositional difference of the volatile components simultaneously from 12 Panax herbal medicines,which included ***(PG),***(PQ),***(PN),red ginseng(PGR),*** leaf(PGL),*** leaf(PQL),*** leaf(PNL),*** flower(PGF),*** flower(PQF),*** flower(PNF),***(PJ),and *** ***(PJvm).Chromatographic separation was performed on an HP-5MS elastic quartz capillary column using helium as the carrier gas,enabling good resolution within 1 *** were able to characterize totally 259 volatile compounds,including 82 terpenes(T),46 alcohols(Alc),29 ketones(K),25 aldehydes(Ald),21 esters(E),and the *** analyzing 90 batches of ginseng samples based on the untargeted metabolomics workflows,236 differential ions were unveiled,and accordingly 36 differential volatile components were *** is the first report that simultaneously compares the compositional difference of volatile components among 12 Panax herbal medicines,and useful information is provided for the quality control of ginseng aside from the well-known ginsenosides.