Rotor hypothesis in the time chain of atrial fibrillation

作     者：Chang-Hao XU Xu LIU 

作者机构：Department of CardiologyShanghai Chest HospitalShanghai Jiao Tong UniversityShanghaiChina 

出 版 物：《Journal of Geriatric Cardiology》 (老年心脏病学杂志（英文版）)

年 卷 期：2022年第19卷第4期

页      面：251-253页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：fibrillation atrial hypothesis 

摘      要：Atrial fibrillation(AF)is the most preval-ent arrhythmia in the aging population,with people over 75 years accounting for 70%of the AF population.[1]Over the past twe-nty years,despite tremendous progress has been made in catheter ablation for rhythm control of AF,we still cannot establish a reliable ablative target for non-paroxysmal *** of the reason is an incomplete understanding of the mechanism underlying the pro-gressive nature of *** the time chain of AF,AF bur-den increases,and the success rate of catheter abla-tion decreases as AF progresses from paroxysmal AF(PAF)to persistent AF(PerAF)and long-stand-ing persistent AF(LS-PerAF)***,with the advance in mapping technologies combined with biophysical insight,a new concept of AF mainten-ance has been introduced--the rotor(spiral waves).Meanwhile,the concept of complete electrical left atr-ial(LA)isolation has been introduced for AF with ext-ensive atrial *** innovative ideas en-riched our armamentarium to combat different AF *** article proposes a rotor hypothesis to illustrate the mechanism underlying AF progress and discuss the application of new strategies in dif-ferent AF subtypes.