The Superior Colliculus:Cell Types,Connectivity,and Behavior
作者机构:Shenzhen Key Lab of Neuropsychiatric ModulationGuangdong Provincial Key Laboratory of Brain Connectome and BehaviorCAS Key Laboratory of Brain Connectome and Manipulationthe Brain Cognition and Brain Disease InstituteShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research InstitutionsShenzhen 518055China University of Chinese Academy of SciencesBeijing 100049China Michael Smith Laboratories and Djavad Mowafaghian Centre for Brain HealthUniversity of British ColumbiaVancouver V6T 1Z4Canada National Institute of Biological SciencesBeijing 100049China
出 版 物:《Neuroscience Bulletin》 (神经科学通报(英文版))
年 卷 期:2022年第38卷第12期
页 面:1519-1540页
核心收录:
学科分类:0710[理学-生物学] 1001[医学-基础医学(可授医学、理学学位)] 07[理学] 071006[理学-神经生物学]
基 金:This review was supported by the Key-Area Research and Development Program of Guangdong Province(2018B030331001) the National Natural Science Foundation of China(31630031 and 31930047) the Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence Fund(2019025),the Guangdong Provincial Key Laboratory of Brain Connectome and Behavior(2017B030301017) the Chinese Academy of Sciences International Partnership Program(172644KYSB20170004) the CAS President’s International Fellowship for Distinguished Scientists(2021DB0003) the Canadian Institutes of Health Research(#10677)
主 题:Superior colliculus Glutamatergic neurons GABAergic neurons Neuronal circuits Innate behaviors
摘 要:The superior colliculus(SC),one of the most well-characterized midbrain sensorimotor structures where visual,auditory,and somatosensory information are integrated to initiate motor commands,is highly conserved across vertebrate ***,cell-type-specific SC neurons integrate afferent signals within local networks to generate defined output related to innate and cognitive *** review focuses on the recent progress in understanding of phenotypic diversity amongst SC neurons and their intrinsic circuits and long-projection *** further describe relevant neural circuits and specific cell types in relation to behavioral outputs and cognitive *** systematic delineation of SC organization,cell types,and neural connections is further put into context across species as these depend upon laminar ***,we focus on SC neural circuitry involving saccadic eye movement,and cognitive and innate ***,the review provides insight into SC functioning and represents a basis for further understanding of the pathology associated with SC dysfunction.