正常妊娠脉波速率的变化及其在预测妊娠期高血压疾病中的价值:一项纵向研究

作     者：Oyama-Kato M. Ohmichi M. Takahashi K. 王淑珍 

作者机构：Department of Obstetrics and GynecologyYamagata University School of MedicineIidanishiYamagataJapan Dr. 

出 版 物：《世界核心医学期刊文摘（妇产科学分册）》 (Core Journal in Obstetrics/Gynecology)

年 卷 期：2006年第2卷第12期

页      面：8-8页

学科分类：1002[医学-临床医学] 100211[医学-妇产科学] 10[医学] 

主　　题：正常妊娠 纵向研究 脉波 妊娠中期 晚期妊娠 妊娠组 妊娠早期 纵向观察 血压监测 研究设计 

摘      要：Objective:We longitudinally examined the changes of brachial to ankle distensibility using pulse wave velocity (PWV)-throughout pregnancy and its difference between normal pregnancy and pregnancy-induced hypertension (PIH) groups. Study design:One hundred and eighty-three pregnant women were included in this study. The PWV examinations were performed in a longitudinal way during the first,second,and third trimesters of pregnancy,and immediately and 1 month after delivery. Results:In normal pregnancies,the PWV significantly decreased at the second trimester,increased from the third trimester through immediately after delivery,and decreased again at 1 month after delivery. In PIH patients,it increased in proportion to the progression of gestation. Conclusion:We monitored the longitudinal changes in PWV and constructed a PWV normogram during pregnancy. The predictive value of PWV and blood pressure for PIH was higher than that of blood pressure alone,suggesting the usefulness of measuring PWV to predict PIH.