MODELING MICROBUBBLE DYNAMICS IN BIOMEDICAL APPLICATIONS

作     者：CHAHINE Georges L. HSIAO Chao-Tsung 

作者机构：DynaflowInc.JessupMaryland 20794USA 

出 版 物：《Journal of Hydrodynamics》 (水动力学研究与进展B辑（英文版）)

年 卷 期：2012年第24卷第2期

页      面：169-183页

核心收录：

学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 08[工学] 0836[工学-生物工程] 0801[工学-力学（可授工学、理学学位）] 

基　　金：supported by the National Institute of Biomedical Imaging and Bioengineering at NIH under SBIR Phase Ⅰ and Phase Ⅱ programs 

主　　题：microbubble biological contrast agents thick shell ultrasound 

摘      要：Controlling microbubble dynamics to produce desirable biomedical outcomes when and where necessary and avoid deleterious effects requires advanced knowledge, which can be achieved only through a combination of experimental and numerical/ analytical techniques. The present communication presents a multi-physics approach to study the dynamics combining viscous- inviscid effects, liquid and structure dynamics, and multi bubble interaction. While complex numerical tools are developed and used, the study aims at identifying the key parameters influencing the dynamics, which need to be included in simpler models.