Significant sensing performance of an all-silicon terahertz metasurface chip for Bacillus thuringiensis Cry1Ac protein

作     者：Zijian Cui Yue Wang Yongqiang Shi Yongqiang Zhu Dachi Zhang Zhiqi Hong Xuping Feng ZIJIAN CUI;YUE WANG;YONGQIANG SHI;YONGQIANG ZHU;DACHI ZHANG;ZHIQI HONG;XUPING FENG

作者机构：Key Laboratory of Ultrafast Photoelectric Technology and Terahertz Science in ShaanxiXi’an University of TechnologyXi’an 710048China Key Laboratory of Engineering Dielectric and Its ApplicationMinistry of EducationHarbin University of Science and TechnologyHarbin 150080China College of Biosystems Engineering and Food ScienceZhejiang UniversityHangzhou 310058China 

出 版 物：《Photonics Research》 (光子学研究（英文版）)

年 卷 期：2022年第10卷第3期

页      面：740-746页

核心收录：

学科分类：08[工学] 080202[工学-机械电子工程] 0802[工学-机械工程] 0703[理学-化学] 

基　　金：Natural Science Foundation of Shaanxi Province(2020JZ-48) Youth Innovation Team of Shaanxi Universities(21JP084) National Natural Science Foundation of China(31801257,61975163) Open Project of Key Laboratory of Engineering Dielectrics and Its Applications,Ministry of Education(KEY1805). 

主　　题：stability process overcome 

摘      要：The promising prospect of a terahertz metasurface in sensing and detection applications has attracted increasing attention because of its ability to overcome the classical diffraction limit and the enhancement of field intensity.In this work,a novel scheme based on an all-silicon terahertz plasmon metasurface is proposed and experimentally demonstrated to be a highly sensitive biosensor for the Bacillus thuringiensis Cry1Ac toxin.The regression coefficients between Bacillus thuringiensis protein concentrations and the spectral resonance intensity and frequency were 0.8988 and 0.9238,respectively.The resonance amplitude variation and frequency shift of the metasurface were investigated in terms of both thickness and permittivity change of the analyte,which reflected the protein residue in the actual process.Moreover,the reliability and stability of the metasurface chip were verified by time period,temperature,and humidity control.These results promise the ability of the proposed metasurface chip as a Bacillus thuringiensis protein sensor with high sensitivity and stability.In addition,this novel device strategy provides opportunities for the advancement of terahertz functional applications in the fields of biochemical sensing and detection.