A simple spectroscopic method for the quantification of gold nanoparticle number concentration in water and fetal bovine serum solutions

作     者：Ruimin Wang Kuan Chen Guanglu Ge 

作者机构：CAS Key Laboratory of Standardization and Measurement for NanotechnologyNational Center for Nanoscience and Technology 

出 版 物：《Chinese Science Bulletin》 (Chin. Sci. Bull.)

年 卷 期：2014年第59卷第16期

页      面：1816-1821页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070302[理学-分析化学] 0703[理学-化学] 

基　　金：supported by Ministry of Science and Technology(2011CB932803) Public Science and Technology Research Project(201210284) 

主　　题：金纳米粒子 粒子数浓度 胎牛血清 水溶液 谱方法 定量化 国民生产总值 定量测定 

摘      要：In this work,we developed a facile and low-cost method with sufficient sensitivity for the quantitative determination of gold nanoparticles(GNPs)number concentration in water and fetal bovine serum *** Au(III)digested from GNPs was reduced to Au(I)presumably by the thiol group of 2-mercaptobenzimidazole,then the Au(I)–thiolate complex was formed,the concentration of which is determined by absorbance at 300 *** number concentration of GNPs can be converted using microscopic images and simple *** interference of serum can be avoided in this *** limit of detection(LOD)of GNPs was calculated as 2.1 910-12mol/L in water solution and 1.3 9 10-11mol/L in fetal bovine serum(FBS)*** method provides a simple and fast way to determine the concentration of GNPs,which can be in carried out in the routine laboratory practice.