Clinical high-risk criteria of psychosis in 8–17-year-old community subjects and inpatients not suspected of developing psychosis

作     者：Frauke Schultze-Lutter Petra Walger Maurizia Franscini Nina Traber-Walker Naweed Osman Helene Walger Benno G Schimmelmann Rahel Flückiger Chantal Michel 

作者机构：Department of Psychiatry and PsychotherapyMedical FacultyHeinrich-Heine UniversityDüsseldorf 40629North-Rhine WestphaliaGermany Department of PsychologyFaculty of PsychologyAirlangga UniversitySurabaya 60286Indonesia University Hospital of Child and Adolescent Psychiatry and PsychotherapyUniversity of BernBern 3000Switzerland Department of Child and Adolescent Psychiatry and PsychotherapyUniversity of ZürichZürich 8032Germany Department of Psychiatry and PsychotherapyLudwig-Maximilian-UniversityMunich 80336BavariaGermany University Hospital of Child and Adolescent PsychiatryUniversity Hospital Hamburg-EppendorfHamburg 20246Germany 

出 版 物：《World Journal of Psychiatry》 (世界精神病学杂志)

年 卷 期：2022年第12卷第3期

页      面：425-449页

核心收录：

学科分类：1002[医学-临床医学] 100205[医学-精神病与精神卫生学] 10[医学] 

基　　金：Supported by the conjoint research grant of the Swiss National Science Foundation,SNSF,No. 144100 the German Research Foundation,DFG,No. 231563730, within the Lead Agency Process (SNSF as exclusive evaluating and approving lead agency) 

主　　题：Psychotic disorders Risk assessment Minors Community Inpatients Psychosocial functioning 

摘      要：BACKGROUND In children and adolescents compared to adults,clinical high-risk of psychosis(CHR)criteria and symptoms are more prevalent but less psychosis-predictive and less clinically *** on high rates of non-converters to psychosis,especially in children and adolescents,it was suggested that CHR criteria were:(1)Pluripotential;(2)A transdiagnostic risk factor;and(3)Simply a severity marker of mental disorders rather than specifically *** any of these three alternative explanatory models were true,their prevalence should differ between persons with and without mental disorders,and their severity should be associated with functional impairment as a measure of *** To compare the prevalence and severity of CHR criteria/symptoms in children and adolescents of the community and *** In the mainly cross-sectional examinations,8–17-year-old community subjects(n=233)randomly chosen from the population register of the Swiss Canton Bern,and inpatients(n=306)with primary diagnosis of attention-deficit/hyperactivity disorder(n=86),eating disorder(n=97),anxiety including obsessive–compulsive disorder(n=94),or autism spectrum disorder(n=29),not clinically suspected to develop psychosis,were examined for CHR symptoms/*** items of the Structured Interview for Psychosis-Risk Syndromes(SIPS)were used to assess the symptomatic ultra-high-risk criteria,and the Schizophrenia Proneness Instrument,Child and Youth version(SPI-CY)was used to assess the 14 basic symptoms relevant to basic symptom *** examined group differences in frequency and severity of CHR symptoms/criteria usingχ^(2) tests and nonparametric tests with Cramer’s V and Rosenthal’s r as effect sizes,and their association with functioning using correlation *** The 7.3%prevalence rate of CHR criteria in community subjects did not differ significantly from the 9.5%rate in *** and severity of CHR criteria never differed bet