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Emerging role of colorectal mucus in gastroenterology diagnostics

作     者:Hesam Ahmadi Nooredinvand Andrew Poullis 

作者机构:Department of GastroenterologySt George's HospitalLondon SW170QTUnited Kingdom 

出 版 物:《World Journal of Gastroenterology》 (世界胃肠病学杂志(英文版))

年 卷 期:2022年第28卷第12期

页      面:1220-1225页

核心收录:

学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主  题:Colorectal mucus Inflammatory bowel disease Crohn's disease Ulcerative colitis Colorectal cancer Faecal calprotectin 

摘      要:Colonoscopy is currently the gold standard for diagnosis of inflammatory bowel disease(IBD)and colorectal cancer(CRC).This has the obvious drawback of being invasive as well as carrying a small *** most widely used non-invasive approaches include the use of faecal calprotectin in the case of IBD and fecal immunochemical test in the case of ***,the necessity of stool collection limits their acceptability for some *** the recent years,there has been emerging data looking at the role of non-invasively obtained colorectal mucus as a screening and diagnostic tool in IBD and *** has been shown that the mucus rich material obtained by self-sampling of anal surface following defecation,can be used to measure various biomarkers that can aid in diagnosis of these conditions.

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