In Silico Analysis of the Cross-Reactivity of Pacific White Shrimp (Litopenaeus vannamei) Allergens with Other Arthropod Species
In Silico Analysis of the Cross-Reactivity of Pacific White Shrimp (Litopenaeus vannamei) Allergens with Other Arthropod Species作者机构：Laboratorio de Inmunología y Biología Molecular Departamento de Recursos del Mar Centro de Investigación y de Estudios Avanzados del IPN Mérida México
出 版 物：《Open Journal of Immunology》 (免疫学期刊（英文）)
年 卷 期：2022年第12卷第1期
页 面：15-39页
学科分类：070902[理学-地球化学] 0709[理学-地质学] 07[理学]
主 题：Allergens Litopenaeus vannamei Allergenicity Immunoglobulin E Food Allergy
摘 要：This study provided new data in the area of cross-reactivity for Pacific white shrimp (Litopenaeus vannamei). Although the cross-reactivity between the most prominent allergenic proteins of shrimp and other crustaceans has been extensively studied, few data are showing the frequency of arthropod-shrimp Litopenaeus vannamei cosensitization in an in silico analysis. A comparative analysis of “typical and non-typical shrimp L. vannamei allergens with other species was achieved, revealing new allergens and previously characterized shrimp allergens, which validated the comprehensive identification approach used in this study. Importantly, up to 192, amino acid sequences were identified that had matches to shrimp L. vannamei allergens that matched allergenic proteins in mites, insects, fish, bacteria, mammals, birds, and plants.
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