Ileocecal lavage fluid for gut microbiota investigation in children with gastrointestinal diseases
作者机构:Key Laboratory of Comprehensive Utilization of Advantage Plants Resources in Hunan SouthCollege of Chemistry and BioengineeringHunan University of Science and EngineeringYongzhouHunanP.R.China State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-productsInstitute of Food ResearchZhejiang Academy of Agricultural SciencesHangzhouZhejiangP.R.China Children’s Hospital of ShanghaiChildren’s Hospital of Shanghai Jiaotong UniversityShanghaiP.R.China
出 版 物:《Gastroenterology Report》 (胃肠病学报道(英文))
年 卷 期:2022年第10卷第1期
页 面:606-608页
核心收录:
学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
基 金:supported by the National Natural Science Foundation of China[No.31800119] the Hunan Natural Science Foundation[No.2020JJ2016,No.2018JJ3200,No.2019JJ40092,No.2019JJ50198] the construct program of applied characteristic discipline in Hunan University of Science and Engineering
摘 要:Introduction The ileocecal region is the end point of colonoscopy and comprises the junction of the ileum,cecum,and *** ileocecal region has been reported as a common lesion site for various intestinal diseases(***’s disease[1],intestinal tuberculosis[2],and primary colorectal lymphoma[3]).However,to date,there have been few studies on the intestinal microbiota of the ileocecal region,because the sampling is relatively difficult and with only a local biopsy it is difficult to represent the whole region without *** with ileocecal mucosa sampling,the collection of ileocecal lavage fluid is easier to be accepted by patients and can avoid the interference of human genomic DNA in the process of bacterial genome sequencing.