Posterior reversible encephalopathy syndrome in a patient with metastatic breast cancer:A case report

作     者：Chae Hyun Song Seung Jun Lee Ha Ra Jeon 

作者机构：Department of Physical Medicine and RehabilitationNational Health Insurance Service Ilsan HospitalGoyang-si Gyeonggi-do 10444South Korea Department of Physical Medicine and RehabilitationNational Health Insurance Service Ilsan HospitalGoyang-si Gyeonggi-do ASI/KR/KS009/GoyangSouth Korea 

出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期：2022年第10卷第7期

页      面：2281-2285页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 100204[医学-神经病学] 10[医学] 

主　　题：Posterior reversible encephalopathy syndrome Breast cancer Hypercalcemia Hypertension Case report 

摘      要：BACKGROUND Posterior reversible encephalopathy syndrome(PRES)is a neurotoxic encephalopathic state with clinical symptoms such as headache,altered consciousness,visual disturbances,and *** edema occurs predominantly in the posterior occipital and parietal lobes of the *** is caused by various diseases,and its mechanism remains ***,it can be easily diagnosed based on characteristic lesions on magnetic resonance *** SUMMARY A 51-year-old woman with unremarkable past medical history presented with progressively worsening back pain since 2 *** examinations revealed paralumbar muscle tenderness,a large lesion on the right breast and several masslike lesions on both *** blood pressure(BP)was elevated(150/90 mmHg),and did not respond to antihypertensive *** the seventh day of hospitalization,she exhibited a confused mental status and generalized tonicclonic *** magnetic resonance imaging,bilateral cortical and subcortical edema of the occipital lobes,suggestive of PRES,was *** serum calcium was 15.8 mg/*** two days of treatment with nicardipine,elcatonin,and zolendronic acid,her BP was 130/91 mmHg and serum calcium was 10.1 mg/*** patient regained consciousness and her mental status ***-positron emission tomography revealed right breast cancer with extensive *** Although rare,hypercalcemia can lead to PRES by causing uncontrolled *** diagnosis can help prevent severe mental disturbances and even death.