A catalysis study of mesoporous MCM-41 supported Schiff base and CuSO_4·5H_2O in a highly regioselective synthesis of 4-thiazolidinone derivatives from cyclocondensation of mercaptoacetic acid

作     者：Hai-Xia Pang Yong-Hai Hui Kui Fan Xue-Jian Xing Yang Wu Jing-Hui Yang Wei Shi Zheng-Feng Xie 

作者机构：Key Laboratory of Oil & Gas Fine ChemicalsMinistry of Education & Xinjiang Uyghur Autonomous RegionCollege of Chemistry and Chemical EngineeringXinjiang University Oil & Gas Field Applied Chemistry Key Laboratory of Sichuan ProvinceSchool of Chemistry and Chemical EngineeringSouthwest Petroleum University 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2016年第27卷第3期

页      面：335-339页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：the National Natural Science Foundation of China(Nos.21162026,21262034 and 21362036) Doctoral Fund of Xinjiang University(No.BS110111)for financial support,Xinjiang University Analytical&Testing Center for instrumental analyses,and Adamas-beta Chemical Co.,for all chemical reagents 

主　　题：MCM 41 Schiff base Cyclocondensation Mercaptoacetic acid Catalysis 

摘      要：Mesoporous MCM-41 supported Schiff base and Cu SO4· 5H2 O shows high catalytic activity in the cyclocondensation of mercaptoacetic acid with imines（or aldehydes and amines） to afford pharmaceutically important thiazolidinone derivatives. The catalytic reactions involving twocomponents or three-components afforded the desired product in high yields（up to 98% and 99%）.Moreover, the catalyst works well with respect to recyclability, giving the product in 85% and 83% yields after recycling six times.