Single skip metastasis in sentinel lymph node: In an early gastric cancer

作     者：Tivadar Jr Bara Simona Gurzu Ioan Jung Zoltan Kadar Haruhiko Sugimura Tivadar Bara 

作者机构：Department of SurgeryUniversity of Medicine and Pharmacy Department of PathologyUniversity of Medicine and Pharmacy Department of Tumor PathologyHamamatsu UniversitySchool of Medicine 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2015年第21卷第33期

页      面：9803-9807页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：Supported by Romanian government,the research project frame POSDRU/159/1.5/S/136893 University of Medicine and Pharmacy of Tirgu-Mures,Romania,the team research project POS-UMFTGM-CC-13-01-V01,No.15/16189/2013 In Japan,funds were obtained by grants from the Ministry of Health,Labour and Welfare(19-19,10103838) Ministry of Education,Culture,Sports,Science and Technology(MEXT)(S-001) 

主　　题：Early gastric cancer Sentinel lymph node Lymph nod 

摘      要：Lymph node status is considered a key prognostic and predictive factor in patients with gastric cancer(GC).Although there is a practical approach to the intraoperative detection of sentinel lymph nodes(SLNs),such a procedure is not included in the European surgical *** this report,we present a practical approach to SLN mapping in a representative case with early gastric cancer(EGC).A 74-year-old female was hospitalized with an endoscopically observed,superficially ulcerated tumor located in the antral *** gastrectomy with D2 lymphadenectomy and SLN mapping was performed by injecting methylene blue dye into the peritumoral submucosal *** incidentally detected blue-stained lymph node located along the middle colic artery was also *** was detected 40 min after injection of the methylene *** examination showed a p T1b-staged well-differentiated HER-2-negative *** of the 41 LNs located at the first,third,and fifth station of the regional LN compartments were found to be free of tumor *** only lymph node with metastasis was located along the middle colicartery and was considered a non-regional lymph *** incidentally identified skip metastasis indicated stage Ⅳ GC.A classic chemotherapy regimen was given,and no recurrences were observed six months after *** this representative case,low-cost SLN mapping,with a longer intraoperative waiting time,totally changed the stage of the tumor in a patient with EGC.