Creatine Supplementation Improves Physical Performance,Without Negative Effects on Health Markers,in Young Weightlifters
作者机构：Laboratory of Physiology and BiokineticFaculty of Biological Sciences and HealthUNIG Campus VItaperuna 28300-000Brazil Departmment of HealthNutritionand Exercise ScienceMessiah UniversityMechanicsburgPA 17837USA Integrative Physiology Research CenterDepartment of Biological SciencesUniversidade Estadual Do Sudoeste da Bahia(UESB)ItaperunaRJ 28300-000Brazil Research Group in Neuromuscular PhysiologyDepartment of Biological SciencesUniversidade Estadual Do Sudoeste da Bahia(UESB)JequiéBA 45210-506Brazil Laboratory of Human Movement StudiesUniversity Foundation of ItaperunaItaperuna 28300-000Brazil
出 版 物：《Journal of Science in Sport and Exercise》 (体育运动科学（英文）)
年 卷 期：2022年第4卷第3期
页 面：255-265页
基 金：First the authors would like to thank all the participants who volunteered to take part in this study. The authors would like to thank all the research assistants involved in this project for their assistance with participant recruitment. The authors'cont
主 题：Supplement Exercise performance Resistance exercise Kidney Liver Safety
摘 要：Purpose The safety of creatine supplementation has been investigated,however,the safety of a high-dose/short-term or low-dose/long-term supplementation dosing scheme,combined with a resistance training program,a commonly used dosing scheme,has not yet *** aim of this study was to evaluate physical performance and the safety of the cited creatine supplementation dosing scheme in a double-blind placebo-controlled study by assessing blood and urine health indicators in subjects undertaking resistance *** Thirty-four healthy male subjects were randomly assigned to creatine supplement(CREA/7 days,0.3 g/kg body mass+21 days,0.03 g/kg)or placebo(PLA)group and both groups participated in a resistance training intervention(6 exercises,3 sets of 8-12 repetitions per exercise at 85%of 1RM,3 d/week).Blood and urine samples were collected pre-,7 and 30 days *** blood(26 parameters)and urine markers(15),between-group differences were calculated by using 2 groups(CREA and PLA)×2 measures(“POST7 minus PREand“POST30 minus PRE)*** The CREA group exhibited significant body weight and 1RM increase(POST30 minus PRE)of all evaluated exercises,when compared to PLA *** the blood and urine health markers,only hematocrit,LDL,Uric Acid,Phosphatase Alkaline and Creatinine exhibited between-group differences,but with small magnitude of differences and maintained into the range of clinical reference *** Our data suggest that creatine supplementation the used dosing scheme,concomitantly with resistance training,improves physical performance with no evident risk or protection to health for young weightlifters.
维普期刊数据库