NFSI-catalyzed S–S bond exchange reaction for the synthesis of unsymmetrical disulfides

作     者：Mengjie Song Qingyue Hu Zheng-Yi Li Xiaoqiang Sun Ke Yang Mengjie Song;Qingyue Hu;Zheng-Yi Li;Xiaoqiang Sun;Ke Yang

作者机构：Jiangsu Key Laboratory of Advanced Catalytic Materials&TechnologySchool of Petrochemical EngineeringChangzhou UniversityChangzhou 213164China Institute of Urban&Rural MiningChangzhou UniversityChangzhou 213164China 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2022年第33卷第9期

页      面：4269-4272页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：the financial support from the National Natural Science Foundation of China (Nos. 21572026, 21702019) Postgraduate Research & Practice Innovation Program of Jiangsu Province (No. SJCX20_0952) Advanced Catalysis and Green Manufacturing Collaborative Innovation Center, Changzhou University 

主　　题：Metal-free Ssingle bond S bond exchange NFSI Unsymmetrical disulfides Organic synthesis 

摘      要：The metal-free S–S bond exchange reaction of symmetrical disulfides catalyzed by NFSI is described. This novel protocol provides a facile and efficient approach to accessing important unsymmetrical ***, this strategy could also be utilized in the late-stage functionalization of amino acids, drugs,and natural products. The broad substrate scope, good functional group tolerance and easy accessibility of catalyst indicate that this strategy affords a green and practical complementary method to various unsymmetrical disulfides.