Emergency treatment of 16 patients with necrotizing fasciitis caused by Vibrio vulnificus infection complicated with septic shock

作     者：Hong Guangliang Wu Bin Lu Caijiao Li Mengfang Zhao Guangju Lu Zhongqiu 

作者机构：Department of Emergency Medicine First Affiliated Hospital of Wenzhou Medical University Wenzhou Zhejiang 325000 China Department of Burns Surgery First AffiliatedHospital of Wenzhou Medical University Wenzhou Zhejiang 325000 China 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2014年第127卷第10期

页      面：1984-1986页

核心收录：

学科分类：100218[医学-急诊医学] 1002[医学-临床医学] 1010[医学-医学技术（可授医学、理学学位）] 10[医学] 

基　　金：This study was supported by the grants from the Key Construction Academic Subject of Zhejiang Province Key Construction Academic Subject of Zhejiang Province 

主　　题：vibrio vulnificus necrotizing fasciitis septic shock therapeutics prognosis 

摘      要：Necrotizing fasciitis （NF） caused by vibrio vulnificus （VV） is a rare but fatal clinical emergency characterized by hemorrhagic bullous skin lesions,septic shock and multiple organ dysfunction syndrome （MODS）,commonly occurring in patients with chronic liver disease.1,2 In general,mortality of these patients is higher than 60%,which could approach 100% when complicated with septic ***,early diagnosis and effectively surgical intervention in emergency room are the mainstays for better outcomes of these ***,many emergency physicians lack experiences in diagnosing and managing vibrio ***,due to the preexisting severe medical complications including hypotension,lactic acidosis,coagulation disorders and thrombocytopenia,the optimal therapeutic strategies for these critical patients should obviously be evaluated on a patient-to-patient basis,which remains largely undefined.