Electrochemical synthesis of dipyrazolo/dipyrimidine-fused pyridines via oxidative domino cyclization of C(sp^(3))–H bonds

作     者：Peng Qian Linna Xu Wenyan Wang Lin Zhang Liang Tang Jiaojiao Liu Liangquan Sheng 

作者机构：School of Chemistry and Material EngineeringEngineering Research Center of Biomass Conversion and Pollution Prevention of Anhui Educational InstitutionsFuyang Normal UniversityFuyangAnhui236037P.R.China 

出 版 物：《Organic Chemistry Frontiers》 (有机化学前沿（英文）)

年 卷 期：2022年第9卷第6期

页      面：1662-1667页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：supported by the Natural Science Foundation of Anhui Province of China(Grant 2108085QB80) Key Program of Educational Commission of Anhui Province of China(Grant KJ2021A0665,KJ2020A0525) the Talent Project of Fuyang Normal University(Grant 2019kyqd0017) the College Students Innovative Entrepreneurial Training Plan Program(Grants S202110371037) 

主　　题：pyridine oxidative pyrimidine 

摘      要：An electrochemically oxidative domino cyclization reaction of methyl azaarenes/ketones with pyrazol-5-amines and 6-amino-pyrimidine-2,4-diones was developed, providing a variety of dipyrazolo[3,4-b:4’,3’-e]pyridines and dipyrimidine-fused pyridines with moderate to good yields. The reaction involved two C–C bond formations and one C–N bond formation in one pot. Moreover, the photoluminescence properties of the representative dipyrazolo[3,4-b:4’,3’-e]pyridines were investigated.