Novel pegiviruses infecting wild birds and rodents

作     者：Wentao Zhu Jing Yang Shan Lu Yuyuan Huang Dong Jin Ji Pua Liyun Liu Zhenjun Li Mang Shi Jianguo Xu Wentao Zhu;Jing Yang;Shan Lu;Yuyuan Huang;Dong Jin;Ji Pu;Liyun Liu;Zhenjun Li;Mang Shi;Jianguo Xu

作者机构：State Key Laboratory of Infectious Disease Prevention and ControlNational Institute for Communicable Disease Control and PreventionChinese Center for Disease Control and PreventionBeijing102206China Shanghai Public Health Clinical CenterFudan UniversityShanghai201508China Research Units of Discovery of Unknown Bacteria and FunctionChinese Academy of Medical SciencesBeijing100730China School of MedicineSun Yat-sen UniversityShenzhen510006China Research Institute of Public HeathNankai UniversityTianjin300071China 

出 版 物：《Virologica Sinica》 (中国病毒学（英文版）)

年 卷 期：2022年第37卷第2期

页      面：208-214页

核心收录：

学科分类：0710[理学-生物学] 090601[农学-基础兽医学] 09[农学] 0906[农学-兽医学] 

基　　金：supported by grants from National Key R&D Program of China(2019YFC1200501 and 2019YFC1200505) Guangdong Province“Pearl River Talent Plan”Innovation and Entrepreneurship Team Project(2019ZT08Y464) Shenzhen Science and Technology Program(KQTD20200820145822023) General Administration of Customs,P.R.China(2019HK125) Research Units of Discovery of Unknown Bacteria and Function(2018RU010) 

主　　题：Bird Rat Pegivirus Evolution Qinghai-Tibet Plateau 

摘      要：Pegivirus(family Flaviviridae)is a genus of small enveloped RNA viruses that mainly causes blood infections in various mammals including ***,we carried out an extensive survey of pegiviruses from a wide range of wild animals mainly sampled in the Qinghai-Tibet Plateau of *** novel pegiviruses,namely Passer montanus pegivirus,Leucosticte brandti pegivirus and Montifringilla taczanowskii pegivirus,were identified from different wild birds,and one new rodent pegivirus,namely Phaiomys leucurus pegivirus,was identified from Blyth s ***,the pegiviruses of non-mammalian origin discovered in this study substantially broaden the host range of Pegivirus to avian ***-evolutionary analysis showed virus-host co-divergence over long evolutionary timescales,and indicated that pegiviruses largely followed a virus-host co-divergence ***,this work extends the biodiversity of the Pegivirus genus to those infecting wild birds and hence revises the host range and evolutionary history of genus Pegivirus.