临床和MRI资料对原发进展型MS远期临床预后的预测价值

作     者：Sastre-Garriga J. Ingle G.T. Rovaris M. A.J. Thompson 王孝文 

作者机构：Prof. Institute of Neurology UCL Queen Square London WC1N 3BG United Kingdom 

出 版 物：《世界核心医学期刊文摘（神经病学分册）》 (Digest of the World Core Medical Journals:Clinical Neurology)

年 卷 期：2005年第1卷第12期

页      面：61-61页

学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学] 

主　　题：预测价值 MRI资料 EDSS 病灶数目 临床评估 状态量 

摘      要：The authors sought to identify clinical and MRI predictors of outcome in primary progressive multiple sclerosis (PPMS). Clinical and MRI assessments were performed at baseline and 2 and 5 years (clinical only). At baseline, disease duration, expanded disability status scale (EDSS) and brain volume predicted outcome. Adding short-term change variables, baseline EDSS, changes in *** load and cord area, and number of new lesions were predictive. Clinical and MRI variables predict long-term outcome in PPMS.