Unusual magnetic resonance imaging findings of brain and leptomeningeal metastasis in lung adenocarcinoma:A case report
作者机构：Department of RadiologyTongde Hospital of Zhejiang ProvinceHangzhou 310012Zhejiang ProvinceChina Department of RadiologyZhejiang Provincial Hospital of Chinese MedicineHangzhou 310012Zhejiang ProvinceChina
出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)
年 卷 期：2022年第10卷第5期
页 面：1723-1728页
核心收录：
学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 100207[医学-影像医学与核医学] 1002[医学-临床医学] 08[工学] 1010[医学-医学技术（可授医学、理学学位）] 100214[医学-肿瘤学] 10[医学]
基 金：Supported by the Medical and Health Science and Technology Planning Project No.2019319609
主 题：Brain metastasis Leptomeningeal metastasis Magnetic resonance imaging Lung cancer Epidermal growth factor receptor Case report
摘 要：BACKGROUND Metastatic tumors are the most common malignancies of central nervous system in adults,and the frequent primary lesion is lung *** and leptomeningeal metastases are more common in patients with non-small-cell lung cancer harboring epidermal growth factor receptor ***,the coexist of brain metastasis with leptomeningeal metastasis(LM)in isolated gyriform appearance is *** SUMMARY We herein presented a case of a 76-year-old male with an established diagnosis as lung adenocarcinoma with gyriform-appeared cerebral parenchymal and leptomeningeal metastases,accompanied by mild peripheral edema and avid contrast enhancement on magnetic resonance *** and pathological examinations confirmed the brain and leptomeningeal metastatic lesions in the left frontal cortex,subcortical white matter and local *** This case was unique with respect to the imaging findings of focal gyriform appearance,which might be caused by secondary parenchymal brain metastatic tumors invading into the leptomeninges or coexistence with *** should be aware of this uncommon imaging presentation of tumor metastases to the central nervous system.
维普期刊数据库