Reinfection and Breakthrough Infection of SARS-CoV-2:An Emerging Challenge That Is Threatening Our World
Reinfection and Breakthrough Infection of SARS-CoV-2: An Emerging Challenge That Is Threatening Our World作者机构：Department of Infectious DiseasesThe Fifth Medical Center of Chinese PLA General HospitalNational Clinical Research Center for Infectious DiseasesBeijing 100039China Peking University 302 Clinical Medical SchoolBeijing 100039China Department of Microbiology&Infectious Disease CenterSchool of Basic Medical SciencePeking University Health Science CenterBeijing 100191China
出 版 物：《Infectious Diseases & Immunity》 (感染性疾病与免疫（英文）)
年 卷 期：2022年第2卷第1期
页 面：29-33页
基 金：This work was supported by Emergency Key Program of Guangzhou Laboratory(EKPG21-30-4) National key research and development plan(2020YFC0860900).
主 题：Breakthrough infections Reinfection SARS-CoV-2 Vaccine
摘 要：The pandemic of coronavirus disease 2019 has threatened humans for more than one and a half years.In particular,viral mutation like delta strain has led to third-or fourth-wave transmission among the countries in Asia,Europe,and North America.Although large-scale vaccination has been carried out in many countries,the incidence of reinfection and vaccine-past breakthrough infection is becoming an emerging challenge to humans worldwide.The related mechanisms underlying the reinfection and breakthrough infection remain unknown.In this review,we summarized the challenge and related reasons for severe acute respiratory syndrome coronavirus 2 reinfection and breakthrough infection.Simultaneously,we addressed some critical contents of the study in future.
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