Cu( II )-Catalyzed C2-site functionalization of p-aminophenols: an approach for selective cross-dehydrogenative aminations

作     者：Xin Zhao Fang Yang Lin-Lin Wang Jing Guo Yu-Qin Xu Zi-Sheng Chen Kegong Ji 

作者机构：College of Chemistry and PharmacyNorthwest A&F UniversityShaanxi Key Laboratory of Natural Products&Chemical Biology3 Taicheng RoadYangling712100 ShaanxiP.R.China School of PharmacyBaotou Medical CollegeBaotou 014060Inner MongoliaP.R.China Guangdong Provincial Key Laboratory of CatalysisSouthern University of Science and TechnologyShenzhen 518055China 

出 版 物：《Organic Chemistry Frontiers》 (有机化学前沿（英文）)

年 卷 期：2022年第9卷第4期

页      面：1010-1015页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：This work was supported by the National Natural Science Foundation of China(NSF-21702170 and 22171228) the Guangdong Provincial Key Laboratory of Catalysis(Grant No.2020B121201002) 

主　　题：smoothly approach bonds 

摘      要：Site selective cross dehydrogenative aminations from precursors without preactivated C–H and N–H bonds have been ***,a copper-catalyzed C2-site selective amination of p-aminophenol derivatives with arylamines has been *** approach precludes both partners from prefunctio-nalization and yields single site selective aminated *** reaction proceeds smoothly with air as a terminal oxidant to produce the corresponding C2-site functional aminophenol derivatives in moderate to good yields.