Cu( II )-Catalyzed C2-site functionalization of p-aminophenols: an approach for selective cross-dehydrogenative aminations
作者机构:College of Chemistry and PharmacyNorthwest A&F UniversityShaanxi Key Laboratory of Natural Products&Chemical Biology3 Taicheng RoadYangling712100 ShaanxiP.R.China School of PharmacyBaotou Medical CollegeBaotou 014060Inner MongoliaP.R.China Guangdong Provincial Key Laboratory of CatalysisSouthern University of Science and TechnologyShenzhen 518055China
出 版 物:《Organic Chemistry Frontiers》 (有机化学前沿(英文))
年 卷 期:2022年第9卷第4期
页 面:1010-1015页
核心收录:
学科分类:081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学]
基 金:This work was supported by the National Natural Science Foundation of China(NSF-21702170 and 22171228) the Guangdong Provincial Key Laboratory of Catalysis(Grant No.2020B121201002)
摘 要:Site selective cross dehydrogenative aminations from precursors without preactivated C–H and N–H bonds have been ***,a copper-catalyzed C2-site selective amination of p-aminophenol derivatives with arylamines has been *** approach precludes both partners from prefunctio-nalization and yields single site selective aminated *** reaction proceeds smoothly with air as a terminal oxidant to produce the corresponding C2-site functional aminophenol derivatives in moderate to good yields.