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Physicochemical properties and antibacterial application of silver nanoparticles stabilized by whey protein isolate

作     者:Aoqiong Zeng Beibei Wang Cheng Zhang Ruijin Yang Shuhuai Yu Wei Zhao 

作者机构:State Key Laboratory of Food Science and TechnologySchool of Food Science and TechnologyJiangnan University1800 Lihu AvenueWuxiJiangsu214122PR China National Engineering Research Center for Functional FoodJiangnan University1800 Lihu AvenueWuxiJiangsu214122PR China 

出 版 物:《Food Bioscience》 (食品生物科学(英文))

年 卷 期:2022年第46卷第2期

页      面:498-506页

核心收录:

学科分类:081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基  金:This work was supported by National Key Research and Development Program of China(2017YFC1601704) National Natural Science Foundation of China(31522044,31671909,31772034,and 31901630) Program of Jiangsu Key Laboratory of Advanced Food Manufacturing Equipment&Technology(FMZ201904) National First-class Discipline Program of Food Science and Technology(JUFSTR20180205) Natural Science Foundation of Jiangsu Province-Youth Program(BK20190583) Fundamental Research Funds for the Central Universities(JUSRP12007) Jiangsu Planned Projects for Postdoctoral Research Funds(2020Z047) 

主  题:Silver nanoparticles Whey protein isolate Chloride Liquid chemical reduction method 

摘      要:Nano metal materials have been widely explored to be applied in medical,environmental,and material *** these nanoparticles,especially silver nanoparticles(AgNPs),have drawn increasing attention for antimicrobial *** researchers are keen on the development of the biologically friendly capping reagents for the synthesis of AgNPs,instead of unfriendly organic *** this study,the liquid chemical reduction method was used to synthesize AgNPs with edible whey protein isolate(WPI)as a capping *** WPI-AgNPs had a broad size distribution(average diameter of 138.6 nm),and their dimensions could be readily controlled in the range of 22.5-149.6 nm by introducing different concentrations of ***,it was confirmed that WPI-AgNPs were formed through two mechanisms,which were respectively reduced in situ(without the addition of NaCl)and ex situ(in presence of NaCl)to yield silver *** WPI-AgNPs synthesized in presence of 10 mM of NaCl as mediation reagent were stable at room temperature or 4℃ up to 3 ***,the synthesized WPI-AgNPs had a good antibacterial activity toward pathogens including Gram-negative *** and Gram-positive *** results shed light on method and capping reagent to stabilize silver nanoparticles,which highlighted the potential of WPI and chloride in metal nanoparticle synthesis.

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