A Systematic Review and Meta-Analysis on Gualou Niubang Decoction for Acute Mastitis

作     者：Tian-tian Gao Shuo Zhang Zhen-lin Chen Miao Wang Hong-yan Wang Wen-jing Ma Lu Wang 

作者机构：Shannxi University of Chinese MedicineXianyang 712046Shannxi ProvinceChina Beijing University of Chinese MedicineBeijing 100029China The Second Affiliated Hospital of Shannxi University of Chinese MedicineXianyang 712000Shannxi ProvinceChina 

出 版 物：《Journal of Clinical and Nursing Research》 (临床护理研究（英文）)

年 卷 期：2022年第6卷第1期

页      面：59-66页

学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学] 

基　　金：General Project of the National Natural Science Foundation of China(No.81974584) 

主　　题：Gualou Niubang decoction Acute mammary mastitis Milk carbuncle Meta analysis 

摘      要：Objective:To systematically evaluate the clinical efficacy of Gualou Niubang decoction in the treatment of acute ***:Randomized controlled trials of Gualou Niubang decoction in the treatment of acute mastitis included in PubMed,Springer,Embase,Cochrane Library,CNKI,Wanfang,Weipu,and China Biomedical Literature Database from January 2016 to *** Cochrane risk bias assessment tool was used to evaluate the risk of *** Revman 5.3 software for Meta ***:There are 8 articles that meet the inclusion criteria,comprising 919 subjects,the test group were 462,cases and control group were 457 *** results of statistical analysis showed that the clinical efficacy of the experimental group was significantly higher than which of the control group,[RR=1.19,95%CI(1.07,1.33),P=0.002],the difference was statistically *** the secondary outcome indicators,compared to the control group,Gualou Niubang decoction can effectively relieve the main symptoms of acute mastitis[MD=-1.96,95%CI(-2.27,-1.65),P0.0001].Gualou Niubang decoction combined with antibiotics can shorten the length of hospital stay[MD=-5.23,95%CI(-6.02,-4.44),P0.00001]and reduce white blood cell count[MD=-2.40,95%CI(-4.71,-0.08),P=0.04]are better than ***:The use of Gualou Niubang decoction to treat acute mastitis can not only improve clinical efficacy,but also effectively relieve clinical symptoms,shorten hospital stay and reduce white blood cell count.