Psychogenic non‑epileptic seizures (PNES)in the context of concurrent epilepsy-making the right diagnosis
作者机构:Department of NeurologyNicosia New General HospitalNicosiaCyprus Department of NeurologyUniversity Hospital of IoanninaIoanninaGreece Medical SchoolUniversity of CyprusNicosiaCyprus Academic Neurology UnitRoyal Hallamshire HospitalUniversity of SheffieldSheffieldUK
出 版 物:《Acta Epileptologica》 (癫痫学报(英文))
年 卷 期:2021年第3卷第1期
页 面:152-162页
学科分类:1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 1009[医学-特种医学] 10[医学]
主 题:PNES Epilepsy Risk factors Diagnosis
摘 要:Epilepsy is a risk factor for the development of psychogenic non-epileptic seizures(PNES)and comorbid epilepsy is recognized as a comorbidity in about 10–30%of patients with *** combination of epileptic and nonepileptic seizures poses a particular diagnostic *** patients with epilepsy,additional PNES may be suspected on the basis of their typical *** possibility of additional PNES should also be considered if seizures fail to respond to antiepileptic drug treatment,in patients with frequent emergency admissions with seizures and in those who develop new types of *** description of semiological details by patients and witnesses can suggest additional *** video recordings can support an initial diagnosis,however,especially in patients with mixed seizure disorders it is advisable to seek further diagnostic confirmation by capturing all habitual seizure types with *** clinical features of PNES associated with epilepsy are similar to those in isolated PNES disorders and include longer duration,fluctuating course,asynchronous movements,pelvic thrusting,side-to-side head or body movement,persistently closed eyes and mouth,ictal crying,recall of ictal experiences and absence of postictal *** can also present as syncope-like episodes with unresponsiveness and reduced muscle *** is no unique epileptological or brain pathology profile putting patients with epilepsy at risk of additional ***,patients with epilepsy and PNES typically have lower educational achievements and higher levels of psychiatric comorbidities than patients with epilepsy *** trauma,including sexual abuse,appears to be a less relevant aetiological factor in patients with mixed seizure disorders than those with isolated PNES,and the gender imbalance(*** greater prevalence in women)is less marked in patients with PNES and additional epilepsy than those with PNES *** sometimes develop after epilepsy surgery.A