Molecular Detection and Identification of Candidatus Ehrlichia Hainanensis,A Novel Ehrlichia Species in Rodents from Hainan Province,China

作     者：ZHAO Hong Qing LIU Pei Pei XUE Feng LU Miao QIN Xin Cheng LI Kun ZHAO Hong Qing;LIU Pei Pei;XUE Feng;LU Miao;QIN Xin Cheng;LI Kun

作者机构：National Institute for Communicable Disease Control and PreventionChinese Center for Disease Control and PreventionBeijing 102206China Chinese Center for Disease Control and PreventionBeijing 102206China Zhejiang Mariculture Research InstituteWenzhou 325000ZhejiangChina 

出 版 物：《Biomedical and Environmental Sciences》 (生物医学与环境科学（英文版）)

年 卷 期：2021年第34卷第12期

页      面：1020-1023页

核心收录：

学科分类：1007[医学-药学(可授医学、理学学位)] 0830[工学-环境科学与工程（可授工学、理学、农学学位）] 100705[医学-微生物与生化药学] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1001[医学-基础医学(可授医学、理学学位)] 100103[医学-病原生物学] 10[医学] 

基　　金：funded by the National Important Scientific&Technology Project [2018ZX10101002-002 and2018ZX10732401-001] the Inner Mongolia Natural Science[grant No. 2016MS0859] the Key Scientific and Technology Project of Inner Mongolia Autonomous Region [grant No. 2021ZD0006] the National Natural Science Foundation of China [grant No. 82102390] 

主　　题：Candidatus Ehrlichia hainanensis Hainan province Niviventer fulvescens 

摘      要：Ehrlichia(Anaplasmataceae family)are obligatory intracellular bacteria that infect humans and *** are hosted by mammals such as canines,bovines and wild rodents,and are vectored by *** this study,we collected 121 rodent samples comprising 67 Niviventer fulvescens,27 Rattus tanezumi,24 Chiromyscus sp.,2 Rattus nitidus and 1 Leopoldamys edwardsi from Hainan province,which includes the second largest island in *** presence and genetic diversity of Ehrlichia species was evaluated and characterized by amplification and sequencing of 16S rRNA,groEL and gltA *** Ehrlichia species was detected in 5 of the 67 Niviventer fulvescens samples(7.46%).The 16S rRNA,groEL and gltA genes showed the highest identity to known Ehrlichia sequences(99.20%,89.87%and 83.86%,respectively).In the phylogenetic trees they formed a cluster distinct from all other *** propose that this species is a putative novel Ehrlichia species,which we suggest be named Candidatus Ehrlichia *** pathogenicity to humans remains to be further researched,and molecular surveillance in local populations is needed.