Limited value of procalcitonin,C-reactive protein,white blood cell,and neutrophil in detecting bacterial coinfection and guiding antibiotic use among children with enterovirus infection

作     者：Rui-Mu Zhang Kun Tan Shu Fu Ji-Kui Deng Rui-Mu Zhang;Kun Tan;Shu Fu;Ji-Kui Deng

作者机构：Department of Infectious DiseasesShenzhen Children’s HospitalShenzhen 518038China 

出 版 物：《World Journal of Pediatrics》 (世界儿科杂志（英文版）)

年 卷 期：2022年第18卷第3期

页      面：230-233页

核心收录：

学科分类：1002[医学-临床医学] 100202[医学-儿科学] 10[医学] 

基　　金：This work was supported by Shenzhen Fund for Guangdong Provincial High-level Clinical Key Specialties[SZGSP012] Project of the Expert Committee on Clinical Application and Drug Resistance Evaluation of Antimicrobial Drugs of the National Health Commission(KJYWZWH-OT-02-2021-01) 

主　　题：enterovirus infection elevated 

摘      要：Procalcitonin(PCT),C-reactive protein(CRP),and white blood cell(WBC)have been used as markers of bacterial infection in children for *** studies have suggested PCT,CRP,WBC,and percentage of neutrophils(%N)may be useful in detecting bacterial infection in children[1-4].However,elevated levels of these biomarkers have also been noted in children with enterovirus infection[5-7].In a study involving 5692 hospitalized children with herpangina or hand,foot,and mouth disease(HFMD)in two periods of years,the medians of CRP were 50.1 and 42.5 mg/L,respectively.