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Neuroimaging brain growth charts:A road to mental health

作     者:Li-Zhen Chen Avram JHolmes Xi-Nian Zuo Qi Dong 

作者机构:State Key Laboratory of Cognitive Neuroscience and LearningBeijing Normal UniversityBeijing 100875China Department of PsychologyYale UniversityNew HavenCT 06511USA Department of PsychiatryYale UniversityNew HavenCT 06511USA National Basic Science Data CenterBeijing 100190China Developmental Population Neuroscience Research CenterInternational Data Group/McGovern Institute for Brain ResearchBeijing Normal UniversityBeijing 100875China Research Center for Lifespan Development of Mind and BrainInstitute of PsychologyChinese Academy of SciencesBeijing 100101China 

出 版 物:《Psychoradiology》 (精神影像学(英文))

年 卷 期:2021年第1卷第4期

页      面:272-286页

学科分类:1002[医学-临床医学] 10[医学] 

基  金:supported by the Child Brain-Mind Development Cohort Study in China Brain Initiative(SQ2021AAA010024) the Start-up Funds for Leading Talents at Beijing Normal University,the National Basic Science Data Center“Chinese Data-sharing Warehouse for In-vivo Imaging Brain”(NBSDC-DB-15) the Beijing Municipal Science and Technology Commission(Z161100002616023) the Major Project of National Social Science Foundation of China(20&ZD296) Dr Avram J.Holmes is supported by the National Institutes of Health(R01MH120080) 

主  题:growth chart development neuroimaging reliability mental health 

摘      要:Mental disorders are common health concerns and contribute to a heavy global burden on our modern *** is challenging to identify and treat them *** evidence suggests the incidence of various psychiatric and behavioral disorders is closely related to the atypical development of brain structure and *** identification and understanding of atypical brain development provide chances for clinicians to detect mental disorders earlier,perhaps even prior to onset,and treat them more *** invaluable and necessary method in identifying and monitoring atypical brain development are growth charts of typically developing individuals in the *** brain growth charts can offer a series of standard references on typical neurodevelopment,representing an important resource for the scientific and medical *** the present paper,we review the relationship between mental disorders and atypical brain development from a perspective of normative brain development by surveying the recent progress in the development of brain growth charts,including four aspects on growth chart utility:1)cohorts,2)measures,3)mechanisms,and 4)clinical *** doing so,we seek to clarify the challenges and opportunities in charting brain growth,and to promote the application of brain growth charts in clinical practice.

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