Comparative transcriptome analysis reveals regional specialization of gene expression in larval silkworm(Bombyx mori)midgut
作者机构：College of Animal SciencesZhejiang UniversityHangzhouChina Key Laboratory of Silkworm and Bee Resource Utilization and Innovation of Zhejiang ProvinceHangzhouChina
出 版 物：《Insect Science》 (昆虫科学（英文版）)
年 卷 期：2022年第29卷第5期
页 面：1329-1345页
核心收录：
学科分类：0710[理学-生物学] 0830[工学-环境科学与工程（可授工学、理学、农学学位）] 07[理学] 08[工学] 09[农学] 0904[农学-植物保护] 071007[理学-遗传学] 0901[农学-作物学] 0836[工学-生物工程] 090102[农学-作物遗传育种] 0713[理学-生态学]
基 金：supported by the National Natural Science Foundation of China(grant numbers 31972619 and 31772675) the Natural Science Foundation of Zhejiang Province(grant number LZ20C170001) support of qRT-PCR analyses from the Experimental Teaching Center,College of Animal Sciences,Zhejiang University
主 题：Bombyx mori gene expression midgut compartmentalization physiological function transcriptome sequencing
摘 要：Insect midgut plays a central role in food digestion and nutrition *** silkworm midgut could be divided into 3 distinct regions based on their morphological ***,it remains rudimentary of regional gene expression and physiological function in larval silkworm *** transcriptome sequencing of 3 midgut compartments,a comprehensive analysis of gene expression atlas along the anterior–posterior axis was *** midgut was found transcriptionally divergent from anterior and middle *** expressed gene analysis revealed the regional specialization of digestive enzyme production,transmembrane transport,chitin metabolism,and hormone regulation in different midgut *** addition,gene subsets of pan-midgut and region-specific transcription factors(TFs)along the length of midgut were also *** results suggested that homeobox TFs might play an essential role in transcriptional variations across the ***,our study provided the first fundamental resource to investigate physiological function and regulation mechanism in larval midgut compartmentalization.
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