Human neuromuscular structure and function in old age:A brief review

作     者：Geoffrey A.Power Brian H.Dalton Charles L.Rice 

作者机构：Human Performance LaboratoryUniversity of Calgary School of KinesiologyThe University of British Columbia Canadian Centre for Activity and AgingSchool of KinesiologyFaculty of Health SciencesThe University of Western Ontario Department of Anatomy and Cell BiologyThe University of Western Ontario 

出 版 物：《Journal of Sport and Health Science》 (运动与健康科学（英文）)

年 卷 期：2013年第2卷第4期

页      面：215-226页

核心收录：

学科分类：1002[医学-临床医学] 100203[医学-老年医学] 10[医学] 

基　　金：supported by an operating grant to Dr.Charles Rice from the Natural Sciences and Engineering Research Council of Canada (NSERC) supported by the Canadian Institutes of Health Research (CIHR) the Michael Smith Foundation for Health Research (MSFHR) supported by Alberta Innovates Health Solutions (AIHS) 

主　　题：Aging Eccentric Force Motor unit Muscle atrophy Power Residual force enhancement Sarcopenia Velocity 

摘      要：Natural adult aging is associated with many functional impairments of the human neuromuscular *** of the more observable alterations is the loss of contractile muscle mass,termed *** loss of muscle mass occurs primarily due to a progressive loss of viable motor units,and accompanying atrophy of remaining muscle *** only does the loss of muscle mass contribute to impaired function in old age,but alterations in fiber type and myosin heavy chain isoform expression also contribute to weaker,slower,and less powerful contracting *** review will focus on motor unit loss associated with natural adult aging,age-related fatigability,and the age-related differences in strength across contractile muscle actions.