Decreased peripheral mtDNA in methamphetamine use disorder

作     者：Ling-Yan Su Yuan Li Qianjin Liu Lijin Jiao Jing Shen Lu-Xiu Yang Ti-Fei Yuan Yong-Gang Yao Ling-Yan Su;Yuan Li;Qianjin Liu;Lijin Jiao;Jing Shen;Lu-Xiu Yang;Ti-Fei Yuan;Yong-Gang Yao

作者机构：Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences&Yunnan Provinceand KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common DiseasesKunming Institute of ZoologyKunming 650204China Kunming College of Life ScienceUniversity of Chinese Academy of SciencesKunming 650204China Shanghai Key Laboratory of Psychotic DisordersShanghai Mental Health CenterShanghai Jiaotong University School of MedicineShanghai 200030China Hubei Shizishan Drug Rehabilitation CenterWuhan 426070China Co-innovation Center of NeuroregenerationNantong UniversityNantong 226019China Translational Research Institute of Brain and Brain-Like IntelligenceShanghai Fourth People’s Hospital Affiliated to Tongji University School of MedicineShanghai 200434China CAS Center for Excellence in Brain Science and Intelligence TechnologyChinese Academy of SciencesShanghai 200031China 

出 版 物：《Science China(Life Sciences)》 (中国科学（生命科学英文版）)

年 卷 期：2022年第65卷第3期

页      面：648-650页

核心收录：

学科分类：0710[理学-生物学] 1007[医学-药学(可授医学、理学学位)] 1006[医学-中西医结合] 100706[医学-药理学] 100602[医学-中西医结合临床] 10[医学] 

基　　金：supported by the Strategic Priority Research Program(B)of CAS(XDB02020003) the National Natural Science Foundation of China(31671050 and 31900695) the Bureau of Frontier Sciences and Education of CAS(QYZDJ-SSW-SMC005) the Youth Innovation Promotion Association,“Light of West China”Program of CAS the Applied Basic Research Foundation of Yunnan Province,Yunnan Department of Science and Technology(202001AT070103) 

主　　题：China Stewart 

摘      要：Dear Editor,Methamphetamine(METH)is the most prevalent addictive psychostimulant in *** use disorder(MUD)and its associated disorders constitute a significant burden to the affected individuals and their families(Paulus and Stewart,2020).Neurotransmitter system aberrations,mitochondrial dysfunction,oxidative stress,and inflammasome activation have been involved in METH-induced neurotoxicity(Shin et al.,2018;Wang et al.,2015;Wei et al.,2020).