Stability of computed tomography densitometry in patients with otosclerosis:a two-year follow-up

作     者：Yanqing Fang Wei Chen Liu-Jie Ren Sebastian Kiehn Yilai Shu Bing Chen Yanqing Fang;Wei Chen;Liu-Jie Ren;Sebastian Kiehn;Yilai Shu;Bing Chen

作者机构：ENT Institute and Otorhinolaryngology Department of the Affiliated Eye and ENT HospitalState Key Laboratory of Medical NeurobiologyFudan UniversityShanghai200031China NHC Key Laboratory of Hearing MedicineFudan UniversityShanghai200031PR China Department of RadiologyEye and ENT HospitalFudan UniversityShanghai200031China Laryngeal Physiology LaboratoryUniversity of Wisconsin e MadisonMadisonWIUnited States Institutes of Biomedical SciencesFudan UniversityNO.83 Fenyang RoadXuhui DistrictShanghai200031China 

出 版 物：《Journal of Otology》 (中华耳科学杂志（英文版）)

年 卷 期：2022年第17卷第1期

页      面：39-45页

核心收录：

学科分类：1002[医学-临床医学] 100213[医学-耳鼻咽喉科学] 10[医学] 

基　　金：supported by National Natural Science Foundation of China(No.81870726) Clinical Research Plan of SHDC(Grant SHDC2020CR4083) 

主　　题：Otosclerosis Fissula ante fenestram(FAF) High reconstruction-computed tomography (HRCT) Auditory CT densitometry 

摘      要：Objectives:To quantify the progression of otosclerosis in the unoperated ear between two stapedotomy procedures for patients with bilateral otosclerosis which can help to determine whether a HRCT scan should be re-performed before the second surgery for patients who already received HRCT imaging before the initial ***:35 patients who underwent bilateral stapedotomy were *** rounds of HRCT examination and audiometry were performed at the time of the first surgery and second surgery on the ear that was not operated on during the initial *** relationship between the changes in HRCT densitometry and audiometry over time was ***:The second round of HRCT did not add significant information about the changes to the otosclerosis lesions in either the imaging diagnosis or the HRCT density values except for small changes in the HRCT densitometry readings at the area anterior to the inner auditory(P=0.01).While the changes in HRCT manifestation are small,changes near the fissula ante fenestram(FAF)were still positively correlated with the air bone gap(ABG)of patients(p=0.031,r=0.388).Conclusions:The progression of lesions in otosclerosis is slow resulting in small and insignificant changes to the HRCT ***,a repeat HRCT evaluations prior to surgery is not necessary for patients who have had a previous HRCT evaluation within 2 years of the *** small changes in HRCT manifestation near the FAF were still correlated with negative effects on the ABG which could cause worsened hearing thresholds over this timeframe。