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Chronic kidney disease: an independent risk factor of all-cause mortality for elderly Chinese patients with chronic heart failure

长期的肾疾病: 为有长期的心失败的老中国病人的所有原因死亡的一个独立风险因素

作     者:Shi-Hui Fu Bing Zhu Yu-Xiao Zhang Shuang-Yan Yi Yuan Liu Tie-Hui Xiao Liang Wang Yong-Yi Bai Cai-Yi Lu Ping Ye Lei-Ming Luo 

作者机构:Department of Geriatric Cardiology Chinese PLA General Hospital Beijing 100853 China Institute of Geriatric Cardiology Chinese PLA General Hospital Beijing 100853 China 

出 版 物:《Journal of Geriatric Cardiology》 (老年心脏病学杂志(英文版))

年 卷 期:2012年第9卷第4期

页      面:355��-360页

核心收录:

学科分类:1002[医学-临床医学] 100210[医学-外科学(含:普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主  题:Chronic heart failure Chronic kidney disease Risk factor The aged 

摘      要:Objective To evaluate the prognostic value of chronic kidney disease (CKD) in elderly Chinese patients with chronic heart failure (CHF). Methods The study consisted of 327 elderly patients with CHF. All-cause mortality was chosen as an endpoint over the median follow-up period of 345 days. Cox regression analysis was used to identify the risk factors of mortality. Results The median age of the entire cohort was 85 years (60��100 years). The mortality for 168 elderly patients with CHF and CKD (51.4% of entire cohort) was 39.9% (67 deaths), which was higher than the mortality for CHF patientswithout CKD [25.2% (40/159 deaths)] and the mortality for entire cohort with CHF [32.7% (107/327 deaths)]. The Cox regression analysis showed that old age [hazard ratio (HR): 1.033; 95% confidence interval (95%CI): 1.004��1.064], CKD(HR: 1.705; 95%CI: 1.132��2.567), CHF New York HeartAssociation (NYHA) class IV (HR: 1.913; 95% CI: 1.284��2.851), acute myocardial infarction (AMI) (HR: 1.696; 95% CI: 1.036��2.777), elevated resting heart rate (HR: 1.021; 95% CI: 1.009��1.033), and decreased plasma albumin (HR: 0.883; 95% CI: 0.843��0.925) were independent risk factors of mortality for elderly patientswith CHF. Conclusions CKDwas an independent risk factor of mortality for elderly Chinese patientswith CHF.

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